产品货号：
Z11976
中文名称：
Bif-1/SH3GLB1抗体
英文名称：
Anti-Bif-1/SH3GLB1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Bif-1/SH3GLB1 Antibody |
| 指标别名 | Bax interacting factor 1;Bif 1;Bif1;Endophilin B1;SH3GLB1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | SH3GLB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | BIF antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BIF.The immunogen is located within the last 50 amino acids of Bif. |
| 计算分子量 | 41kDa |
| 成分 | Bif Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Bif Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis plays a major role in normal organism development,tissue homeostasis,and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases.Proteins that comprise the Bcl-2 family such as Bax appear to control the activation of these enzymes.Bax activity was found to be regulated by its association with Bax-interacting factor 1 (BIF),a member of the endophilin B family that is associated with intracellular membranes.Following this interaction,Bax undergoes a conformational change and translocates to mitochondrial membranes.The Bax/BIF interaction appears to be enhanced by apoptotic stimuli,suggesting that BIF acts as the trigger to activate Bax,and as suppression of BIF promoted HeLa cell colony formation in soft agar,it may have a role in the suppression of cancer progression.At least two isoforms of BIF are known to exist. |
| Uniprot ID | Q9Y371 |
| 基因名全称 | SH3-domain GRB2-like endophilin B1 |
| 蛋白名全称 | SH3-domain GRB2-like endophilin B1 |
| 推荐稀释比 | BIF antibody can be used for the detection of BIF by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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